DÉRIVÉS ACTIFS DE 3,4-DIHYDRO-2H-PYRAZINO[1,2-A]INDOL-1-ONE EN TANT QU'INHIBITEURS DE KINASE, PROCÉDÉ POUR LEUR PRÉPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

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专利权人:

NERVIANO MEDICAL SCIENCES S.R.L.

发明人:

申请号：

EP09724061.8

公开号：

EP2254886B1

申请日:

2009.03.27

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Compounds which are 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed； these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders； also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

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