ILAGAN ROGER,JAYO MANUEL J,JAIN DEEPAK,LUDLOW JOHN W,GENHEIMER CHRISTOPHER,BASU JOYDEEP,KNIGHT OLUWATOYIN,PAYNE RICHARD,SANGHA NAMRATA,GUTHRIE KELLY I,BERTRAM TIMOTHY A,QUINLAN SARAH F,RAPOPORT H SCOT
申请号：
NZ62641909
公开号：
NZ626419A
申请日:
2009.11.04
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed is an implantable construct for replacement of a defective bladder in a subject comprising a) a tubular scaffold having a first open end configured for anastomosis to an opening in the subject&rsquos abdominal wall, a second open end configured to connect to a ureter and b) an autologous smooth muscle cell (SMC) population that is not derived from the defective bladder, deposited on or in a surface of the tubular scaffold, wherein the cell population is a smooth muscle cell population derived from adipose tissue or peripheral blood, and wherein the implantable construct is adapted for temporary storage and passage of urine.
