Paiman Peter Ghoroghchian,Ruogu Qi,Angela M. Belcher,Xiangnan Dang,Zhimin Tao
申请号：
US15584516
公开号：
US20180008687A1
申请日:
2017.05.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are methods of treating cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents. In addition, nanoparticles are described that comprise a highly toxic anticancer agent (e.g., an anticancer agent having an IC50 less than 1 nM) covalently bound via a linker to a triblock copolymer. Other nanoparticles that comprise Pt(IV) and an anticancer agent are also described. Also disclosed are nanoparticles comprising imaging agents non-covalently associated with a polymer, and methods of imaging cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents.
