Board of Regents of the University of Texas System;University of Iowa Research Foundation
发明人:
申请号：
EP14860562.9
公开号：
EP3068388A4
申请日:
2014.11.11
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Provided herein are compositions and methods for reducing one or both of axonal degeneration and neuronal cell death associated with a disease or traumatic brain injury. An aminopropyl carbazole agent with potent neuroprotective properties is described. Specifically, (−)-(S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine, is proposed as a new pharmacological agent for protecting patients against axonal degeneration and chronic consequences of TBI.
