Topical pharmaceutical or cosmetic compositions are described comprising octenidine dihydrochloride. Said compositions are stable and can be safely and easily applied over large surface areas of the skin in an acceptable way by the general patient population for the treatment or prevention of some skin disorders or diseases.一種局部醫藥組成物或化妝品組成物,其包含奧替尼啶二鹽酸鹽。該等組成物為穩定的,且可安全地且易於以一般患者群體可接受之方式塗敷於皮膚之大表面區域上,以便治療或預防一些皮膚病症或疾病。