Marzena Mazur,Robert Koralewski,Bartlomiej Borek,Sylwia Olejniczak,Wojciech J. Czestkowski,Michal C. Piotrowicz,Jacek P. Olczak,Adam A. Golebiowski,Agnieszka Bartoszewicz,Elzbieta Maziarz,Michal L. Ko
申请号：
US16277321
公开号：
US10538508B2
申请日:
2019.02.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
