MAZUR, MARZENA,KORALEWSKI, ROBERT,BOREK, BARTLOMIEJ,OLEJNICZAK, SYLWIA,CZESTKOWSKI, WOJCIECH J.,PIOTROWICZ, MICHAL C.,OLCZAK, JACEK P.,GOLEBIOWSKI, ADAM A.,BARTOSZEWICZ, AGNIESZKA,PLUTA, ELZBIETA,KOWA
申请号：
CA2997382
公开号：
CA2997382A1
申请日:
2016.09.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
