A method of inflammatory conditions that treating subject, including the nucleic acid molecules to subject with this need application for inhibiting Hom-1 to express. Specifically, nucleic acid molecules are RNAi agent or antisense morpholino oligonucleotides. Further disclose the method for selecting therapeutic agent for the inflammatory conditions of subject, or the method for monitoring the effect of therapeutic agent is to inflammatory conditions in subject, the expression including detecting the Hom-1 from Inflamed tissues sample that subject obtains.