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Method for preparing chitosan matrices having improved mechanical properties
专利权人:
发明人:
申请号:
EP14306484.8
公开号:
EP3000488A1
申请日:
2014.09.26
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to a method for preparing a chitosan matrix having good mechanical properties comprising the steps of- a) preparing a solution of chitosan,- b) pouring the solution of a) into a mould in order to form a layer,- c) lyophilizing the layer of b) in order to obtain a matrix of chitosan,- d) sterilizing the matrix obtained in c) by water vapor treatment.The invention also relates to the matrices obtained and to surgical implants comprising such matrices.The invention further relates to a method for increasing the suture retention strength of a chitosan matrix obtained by lyophilization of a chitosan solution, and to a method for for decreasing the solubilization rate in hydrochloric acid of a chitosan matrix obtained by lyophilization of a chitosan solution, comprising the step of sterilizing said matrix by a water vapor treatment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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