Method and kit for detecting phospholipid hydroperoxide dependent cell death, inhibitor of phospholipid hydroperoxide dependent cell death, and prevention or treatment of cardiac insufficiency or arrhythmia sudden death
PROBLEM TO BE SOLVED: To provide a detection method and kit for phospholipid hydroperoxide-dependent cell death, a protein and nucleic acid, a phospholipid hydroperoxide-dependent cell death inhibitor, and a preventive or therapeutic agent for diseases by clarifying a factor involved in a cell death pathway caused by PHGPx depletion.SOLUTION: The invention provides a detection method for phospholipid hydroperoxide-dependent cell death having a step of detecting the production of phospholipid hydroperoxide and the activation of Abhd2 in a cell sample.SELECTED DRAWING: Figure 27