PROBLEM TO BE SOLVED: To provide a method for treating brain cancer. A method comprising administering an effective amount of a compound of formula VIII having a (substituted phenyl)propenal moiety. [Wherein R18 and R28 are mono- or di-substituted methoxy groups, hydroxyl groups, or alkylsulfonyl groups; R38 or R48 is H, CH3, F, Cl, or a specific substituent, and n8 is 1 Or represents an integer of 2] [Selection diagram] None【課題】脳癌の治療方法の提供。【解決手段】有効量の、(置換フェニル)プロペナール部分を有する式VIIIの化合物を投与することを含む方法。[式中、R18及びR28は、モノ-又はジ-置換されたメトキシ基、ヒドロキシル基、又はアルキルスルホニル基;R38又はR48は、H、CH3、F、Cl、又は特定の置換基、n8は1又は2の整数を表す]【選択図】なし