The present invention provides a drug showing liver protection, detoxification, lipid-lowering and hypoglycemic properties and use thereof, which is a formulation prepared from a starting material comprising, in parts by weight, 10-35 parts of the root of Trichosanthes cucumeroides (Ser.) Maxim, 5-20 parts of the root of Radix Sophorae Flavescentis, 15-30 parts of Tartary Buckwheat, 15-25 parts of the root of Rhizoma Dioscorea, 10-35 parts of the root of Kudzu Vine and 10-25 parts of pollen. It is useful in the manufacturing of a medicament for treating liver diseases, in the manufacturing of a medicament for treating hyperlipidemia or in the manufacturing of a medicament for treating diabetes. The drug of the present invention takes advantages of the medicinal properties of the root of Trichosanthes cucumeroides (Ser.) Maxim and the root of Radix Sophorae Flavescentis, to achieve liver-clearing and cholagogue effects, and a therapeutical effect on jaundice and chronic hepatitis, in combination with the spleen-nourishing, Qi-regulating, pathogenic wind-dispelling and phlegm-eliminating properties of Tartary Buckwheat, the spleen-nourishing, appetizing, deficiency restoring properties of the root of Rhizoma Dioscorea, the deficient heat clearing and alcoholism relieving properties of the root of Kudzu Vine, and the thirst relieving and jaundice clearing properties of pollen. Thus, liver protection, detoxification, lipid-lowering and hypoglycemic effects can be achieved by the drug of the present invention. The drug of the present invention further provides the following advantages: its raw materials can be obtained from abundant sources； its formulation can be prepared using conventional processes, through simple procedures, and at a low cost； it is much worthy of promotion and application, and has a promising market prospect and a vast space for development.
