LI YINGCHUN,DOMINIC J. AMBROSI,GU JIJIE,JONATHAN A. HICKSON,DEANNA L. HAASCH,GUPTA SUPRIYA,CHARI RAVI,ZAMIRI CAMELLIA,SUSAN E. LAPPE,NAUMOVSKI LOUIE,COA XIANHUA
申请号:
UY35110
公开号:
UY35110A
申请日:
2013.10.31
申请国别(地区):
UY
年份:
2014
代理人:
摘要:
In the present report multiespecificas multivalent binding proteins and Methods of making, binding proteins, and their use in the diagnosis, Monitoring, Treatment or inhibiciony / cancer, Tumors, and / or other angiogenesis dependent diseases that are characterized by expression or act Aberrant ivity of Dll4 and / or VEGF.En la presente se divulgan proteinas de union multivalentes y multiespecificas, metodos de hacer las proteinas de union, y sus usos en el diagnostico, monitoreo, inhibiciony/o tratamiento de cancer, tumores, y/u otras enfermedades dependientes de angiogenesis que se caracterizan por expresion o actividad aberrante de DLL4 y/o VEGF.