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RAPIDLY DISINTEGRATING FILMS FOR DELIVERY OF PHARMACEUTICAL OR COSMETIC AGENTS
专利权人:
Inc.;Adhesives Research
发明人:
Scott D. Barnhart,Andrew P. Full,Cathy M. Moritz
申请号:
US13709775
公开号:
US20130095156A1
申请日:
2012.12.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides disintegratable films containing a mixture of high molecular weight and low molecular weight water soluble components; and a pharmaceutically or cosmetically active ingredient. Optionally, the films contain a starch component, a glucose component, a filler, a plasticizer and/or humectant. The films are preferably in the form of a mucoadhesive monolayer having a thickness sufficient to rapidly disintegrate in the oral environment and release the active ingredient without undue discomfort to the oral mucosa. The monolayer can be cut to any desired size or shape to provide conveniently useable unit dosage forms for administration to oral or other mucosal surfaces for human pharmaceutical, cosmetic, or veterinary applications. The invention further provides methods of administering the film compositions by placing the composition into, for example, the oral cavity for a sufficient period of time to permit the film to disintegrate and release the active ingredient.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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