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Method of screening of therapeutic agents for K-Ras mutant driven cancers
专利权人:
发明人:
Bum Joon Park,Nam Chul Ha,Sun Hye Lee,Gyu Yong Song,Jee Hyun Lee
申请号:
US14144603
公开号:
US09400281B2
申请日:
2013.12.31
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or prevention of K-Ras mutant cancer, such as, pancreatic cancer, lung cancer, cholangioma, and colon cancer, of which diagnosis or treatment is not easy.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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