PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
发明人:
PARK, BUM JOON,HA, NAM CHUL,LEE, SUN HYE,SONG, GYU YONG,LEE, JEE HYUN
申请号:
EP09827769
公开号:
EP2377849A4
申请日:
2009.11.23
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or prevention of K-Ras mutant cancer, such as, pancreatic cancer, lung cancer, cholangioma, and colon cancer, of which diagnosis or treatment is not easy.