Embodiments described herein provide ophthalmic surgical instruments. One embodiment provides an instrument including an infusion sleeve, aspiration tube, and infusion/aspiration tip. The sleeve can include a body defining an infusion channel. The tube can be in the fusion channel and define an aspiration channel. The tip can deform to the distal end of the tube. The tip can seal a gap between the sleeve and tube and can include a flange with a profile(e.g., a tapered portion) corresponding to the profile of the sleeve. The sleeve and tip can be keyed such that the sleeve directs fluid in one direction and the tip draws fluid perpendicularly from that direction. The tip's aspiration channel can extend distally beyond its aspiration port. The tip can extend to a point adjacent to an infusion port of the sleeve. A disposable component (including an aspiration tube and infusion/aspiration tip) for use with instrument is provided.於此描述之實施例係提供一種眼科用手術儀器。其中一實施例係提供一種包含灌注套管、抽吸管,以及灌注/抽吸尖頭之儀器。該灌注套管包含一定義出灌注通道之主體。抽吸管可位於灌注通道內,並定義出抽吸通道。尖頭可與抽吸管末端吻合。尖頭可密封灌注套管與抽吸管間的空隙,並可於側面(如斜形部分)包含一凸緣,對應於灌注套管之側面。灌注套管與尖頭可互相嵌合,使得灌注套管可於某一方向引導流體,而尖頭則於該方向之垂直方向上吸出流體。尖頭之抽吸通道可向末端延伸至抽吸口。該尖頭可延伸至灌注套管灌注口之鄰近點上。亦提供該儀器所使用之拋棄式組件(包括抽吸管與灌注/抽吸尖頭)。