A compound having the structure set forth in Formula (I) or Formula (II):wherein the variables Y, R1, R2, R3, and R4are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.一種化合物具有如式(I)或式(II)所示之結構：其中Y、R1、R2、R3及R4如此處所定義。此處所提供的是聚(ADP-核糖)聚合酶的抑制物。此處亦揭露醫藥組成物包括至少一種此處所述之化合物，以及使用該化合物或此處所述之醫藥組成物用以治療可藉由抑制PARP活性而改善的疾病、失調及病狀。
