THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
LIBUTTI, STEVEN K.,KWON, MIJUNG,TANDLE, ANITA
申请号：
CA2706317
公开号：
CA2706317C
申请日:
2008.12.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A purified DOC1 polypeptide comprising a fragment of SEQ ID NO: 1 is provided,wherein the DOC1 polypeptide is not the full-length DOC1 polypeptide sequence.Amethod of inhibiting angiogenesis in a subject is provided comprisingadministering to asubject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in thesubject producesthe DOC1 polypeptide, thus inhibiting angiogenesis. A method of inhibitingtumor growthin a subject is provided comprising administering to a subject a nucleic acidencoding aDOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide,thusinhibiting tumor growth.
