The United States of America as Represented by the Secretary of the Department of Health and Human S
发明人:
Steven K. Libutti,Mijung Kwon,Anita Tandle
申请号：
US15058116
公开号：
US20160176935A1
申请日:
2016.03.01
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A purified DOC1 polypeptide comprising a fragment of SEQ ID NO: 1 is provided, wherein the DOC1 polypeptide is not the full-length DOC1 polypeptide sequence. A method of inhibiting angiogenesis in a subject is provided comprising administering to a subject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide, thus inhibiting angiogenesis. A method of inhibiting tumor growth in a subject is provided comprising administering to a subject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide, thus inhibiting tumor growth.
