PERKINS WALTER,MALININ VLADIMIR,LI XINGONG,MILLER BRIAN,SEIDEL DOMINIQUE,HOLZMANN PHILIPP,SCHULZ HARALD,HAHN MICHAEL
申请号：
NZ70098313
公开号：
NZ700983A
申请日:
2013.05.21
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Provided herein are systems for treating a subject with a pulmonary infection, for example, a nontuberculous mycobacterial pulmonary infection, a Burkholderia pulmonary infection, a pulmonary infection associated with bronchiectasis, or a Pseudomonas pulmonary infection. The system includes a pharmaceutical formulation comprising a liposomal aminoglycoside dispersion, and the lipid component of the liposomes consist essentially of electrically neutral lipids. The system also includes a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 gram per minute. The aerosol is delivered to the subject via inhalation for the treatment of the pulmonary infection.
