A system for image alignment includes an alignment mechanism (132) configured to permit user alignment of images. A first imaging modality (110) is configured to concurrently provide images in two imaging planes using an imaging mechanism (134) associated with the alignment mechanism (132). An image processing module (126) is configured to display first images collected with the first imaging modality and second images collected with a second imaging modality (130) to permit user alignment using the alignment mechanism between the first images and the second images in multiple planes. A registration module (115) is stored in memory and configured to register the first images with corresponding second images in the multiple planes when alignment in the multiple planes has been achieved.