To provide a pharmaceutical composition for treating multiple myeloma. After investigating compounds having a mitochondrial Complex I inhibitory effect, the present inventor completed the present invention by confirming that the bicyclic nitrogen-containing aromatic heterocyclic amide compounds of the present invention have a mitochondrial Complex I inhibitory effect, and that these compounds have a growth inhibition effect on multiple myeloma.提供多發性骨髓瘤之治療用醫藥組成物。本發明者們檢討具有線粒體Complex I阻礙作用的化合物,確認本發明之二環式含氮芳香族雜環醯胺化合物具有線粒體Complex I阻礙作用,且此等的化合物具有多發性骨髓瘤之增殖抑制作用,而完成本發明。
