The present invention provides a novel compound having an agonist action at AT2receptor and expected as a pharmaceutical product, and also provides a method of treating or preventing various diseases.The novel sulfonyl malonamide derivative, or a pharmacologically acceptable salt thereof or a solvate thereof of the present invention has therapeutic and/or preventive effect(s) on various diseases due to its agonist action at AT2receptor, and is useful as a pharmaceutical agent for the treatment and/or prevention of diseases involving the renin-angiotensin-aldosterone system (RAAS).本發明提供對AT2受體具有促效劑作用且預期可作為醫藥產品之新穎化合物，本發明亦提供治療或預防多種疾病之方法。由於本發明之新穎磺醯基丙二醯胺衍生物、或其醫藥上可接受之鹽或其溶劑合物，對AT2受體具有促效劑作用，因此其對多種疾病具有治療及/或預防效果，且可使用作為醫藥劑以用於治療及/或預防與腎素-血管收縮素-醛固酮系統(renin-angiotensin-aldosterone system； RAAS)相關之疾病。
