In a vertebral body replacement implant having a bottom locating part for positioning against a lower vertebral body and having a top locating part for positioning against an upper vertebral body, wherein both locating parts are steplessly displaceable relative to one another along a displacement path so that the height of the vertebral body replacement implant is variable, having a clamping device for fixing the two locating parts in any desired intermediate position along the displacement path, which clamping device comprises a clamping element that is mounted on one locating part so as to be variable in position and can be pressed towards a clamping face on the other locating part, in order to improve the clamping action it is proposed that the clamping face is inclined slightly relative to the displacement path, so that when the locating parts are pushed together the clamping face moves progressively closer to the clamping element.