The present invention is a method of making excipient free N-Acetylglucosamine tablets and also the excipient free N-Acetylglucosamine tablets in a variety of sizes, in particular 10 gram tablets. These excipient free tablets are palatable and suitable for consumption by horses, smaller animals and humans. In the method of making these tablets, of N-Acetylglucosamine powder is mixed with a specific amount of water, to bring about a moldable mass which is formed into suitably sized tablets through compression in a tablet mold. The solvent water is then allowed to evaporate leaving behind an excipient free N-Acetylglucosamine tablet.