Michael D. West,Karen B. Chapman,Roy Geoffrey Sargent
申请号：
US14525378
公开号：
US10501723B2
申请日:
2014.10.28
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This invention generally relates to methods to obtain mammalian cells and tissues with patterns of gene expression similar to that of a developing mammalian embryo or fetus, and the use of such cells and tissues in the treatment of human disease and age-related conditions. More particularly, the invention relates to methods for identifying, expanding in culture, and formulating mammalian pluripotent stem cells and differentiated cells that differ from cells in the adult human in their pattern of gene expression, and therefore offer unique characteristics that provide novel therapeutic strategies in the treatment of degenerative disease.
