BILODEAU MARK T,KADIYALA SUDHAKAR,SHINDE RAJESH,WHITE BRIAN,WOOSTER RICHARD,BARDER TIMOTHY EDWARD
申请号：
IN4722/DELNP/2015
公开号：
IN2015DN04722A
申请日:
2015.06.01
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Particles, including nanoparticles and microparticles , and pharmaceutical formulations thereof , containing conjugates of an active agent such as a therapeutic, prophylactic , or diagnostic agent attached to a targeting moiety via a linker have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates , the particles , and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example , to treat or prevent cancer or infectious diseases.
