The invention relates to a composition which induces, in a host, a cytotoxiccell response directed against cells expressing an antigen, in particulartumour cells, and which comprises red blood cells containing said antigen.These red blood cells may be in the form of an immune complex with animmunoglobulin, in particular IgG, which recognizes an epitope at thesurface of the red blood cells, and/or be heat-treated or chemically treatedso as to promote phagocytosis of said red blood cells by dendritic cells. As avariant, the red blood cells may be xenogenic red blood cells. The inventionalso relates to a therapeutic especially anti-tumour vaccine containing sucha composition.
