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ß2-adrenergic receptor agonist to improve scar skin color matching
专利权人:
UNIVERSITY OF LEICESTER
发明人:
Christine Elaine PULLAR
申请号:
BR112015021668
公开号:
BR112015021668A2
申请日:
2014.03.07
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
Patent Summary for: "β2-adrenergic receptor antagonist to improve scar skin color matching". a method for improving scar skin color matching, for example, by reducing scar hyperpigmentation, the method comprising administering a therapeutically effective amount of an agent, which positively modulates β2-adrenergic receptor conformation, or receptor activity, or activation thereof, to an individual in need thereof. The individual is typically in need of improving scar skin color matching, for example by reducing scar hyperpigmentation, because the individual has or is at risk for hyperpigmentation. The individual is typically selected to be at risk for hyperpigmentation based on one or more of the following factors: • The individual had previously developed hyperpigmentation of a scar • The individual tans readily when exposed to the sun or ultraviolet (uv) radiation instead of burning the individual has a non-Caucasian racial originâ € ¢ the skin color of the individual (for example, in a area that is not tanned) is said to be darker than typical for a fair-haired Caucasian person. the individual may be selected as being at risk of hyperpigmentation because they are at least predominantly Chinese, African black, Asian or South European and / or if their skin type can be assessed according to the fitzpatrick scale as type iii, iv, v or vi.resumo da patente de invenã§ã£o para: “agonista de receptor î²2-adrenã‰rgico para melhorar a correspondãšncia de cor de pele de cicatrizâ€�. um mã©todo para melhorar a correspondãªncia de cor de pele de cicatriz, por exemplo, reduzindo a hiperpigmentaã§ã£o de cicatriz, o mã©todo compreendendo a administraã§ã£o de uma quantidade terapeuticamente eficaz de um agente, o qual modula positivamente conformaã§ã£o de receptor î²2-adrenã©rgico, ou a atividade do receptor, ou a ativaã§ã£o dos mesmos, a um indivã­duo em necessidade dos mesmos. o indivã­duo tipicamente estã¡ em necessidade de melhorar a correspondãªncia de cor de pele de ci
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