CHILDREN'S MEDICAL CENTER CORPORATION;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;DANA-FARBER CANCER INSTITUTE, INC.;THE TECHNICAL UNIVERSITY OF DENMARK
发明人:
Zoltan I. Szallasi,Andrea L. Richardson,Nicolai J. Birkbak,Zhigang Wang
申请号:
US16404204
公开号:
US20190309373A1
申请日:
2019.05.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides assays, methods and systems for selecting an effective therapy for a subset of cancer patients having cancer cells with increased expression of BML and FANCI genes and/or having copy number increase in chromosome location 15q26 in the cancer cells and for treatment of such patients with the effective therapy of cancer patients based on the personalized cancer cell expression profile.