Juan Carlos Lacal SanJuan,Ana Ramirez De Molina,David Gallego Ortega
申请号：
US14509349
公开号：
US20150098927A1
申请日:
2014.10.08
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to methods for the treatment of cancer based on the induction of the choline kinase beta (hereinafter ChoKβ) activity as well as to methods for the design of personalized therapies and for determining the response of an agent capable of inducing choline kinase beta (hereinafter ChoKβ) for the treatment of cancer as well as to methods for determining the prognosis of a patient based on the determination of the ChoKβ expression levels as well as based on the determination of the relationship between the ChoKβ and ChoKα expression levels. Finally, the invention relates to methods for determining the response of a patient who suffers from cancer to ChoKα-inhibiting agents based on the determination of the PEMT and/or ChoKβ expression levels.
