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TREATMENT OF AUTISM
专利权人:
SYNAPTEC DEVELOPMENT LLC
发明人:
Bonnie M. DAVIS
申请号:
US15129068
公开号:
US20170173038A1
申请日:
2015.03.24
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Autistic Spectrum Disorders (ASD) are a group of developmental disorders including autistic disorder, Asperger disorder and pervasive developmental disorder not otherwise specified which may be treated by use of a galanthamine analog wherein the hydroxy group of galantamine is replaced by a carbamate, carbonate or ester group and the metboxy group may be replaced by another alkoxy group of from two to six carbon atoms, a hydroxy group, hydrogen, an alkanoyloxy group or 2 to 10 carbon atoms, a benzoyloxy or substituted benzoyloxy group, a carbonate group of 1 to 10 carbon atoms or a carbamate group such as a mono alkyl or dialkyl or an aryl carbamate wherein the alkyl groups or aryl groups contain from 1 to 10 carbons, and the N-methyl group may be replaced by hydrogen, alkyl of 1 to 10 carbon atoms, benzyl, cyclopropylmethyl group or a substituted or unsubstituted benzoyloxy group. Galantamine mon-alkylcarbamates are particularly useful.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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