2, 4-PYRIMIDINEDIAMINES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY AND IMMUNE SYSTEM DISORDERS

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专利权人:

NOVARTIS AG

发明人:

GARCIA-ECHEVERRIA CARLOS,KANAZAWA TAKANORI,KAWAHARA EIJI,MASUYA KEIICHI,MATSUURA NAOKO,MIYAKE TAKAHIRO,OHMORI OSAMU,UMEMURA ICHIRO,STEENSMA RUO,CHOPIUK GREG,JIANG JIQING,WAN YONGQIN,DING QIANG,ZHANG Q

申请号：

SI200431849

公开号：

SI1660458T1

申请日:

2004.08.13

申请国别(地区):

SI

年份:

2012

代理人:

摘要：

Novel pyrimidine derivatives of formula (I) and their use for the manufacture of a medicament for the treatment or prevention of a disease which responds to inhibition of FAK and/or ALK and/or ZAP-70 and/or IGF-IR. in which: n is selected from 1,2 and 3 R 1 is selected from phenyl, pyridinyl, pyrazolyl and pyrimidinyl and R 2 and R 3 are as described herein.

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