A method and apparatus to deliver biological altering substances through body cavities including ears, nose, mouth, anus and vagina, utilizing at least osmotic, olfactory and inhaling transfusion of active ingredients includes a first reservoir configured to be disposed against sublingual surfaces and hold a first drug. The device is configured to transmit the first drug through sublingual surfaces into the bloodstream. A second reservoir, coupled to the first reservoir, is disposed below a nostril, and configured to hold a substance and transmit the substance into air passing from the exterior of the nostril into the nasal cavity.