РОСС Кельвин Джон (умер),СЭМС Мартин Джеймс (GB),ХАЙ Джулиет Виктория (GB),ДЖЕЙМИСОН Пол Эндрю (GB)
申请号：
RU2012155117/15
公开号：
RU2012155117A
申请日:
2011.06.29
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. Pharmaceutical composition for sublingual opioid delivery containing an opioid and ethanol. 2. The composition according to claim 1, which further comprises glycerin. 3. The composition of claim 1, wherein the opioid is not fentanyl. The composition of claim 1, wherein said opioid is methadone. The composition according to claim 1, which is contained in the container, and where the substance of the container that is in contact with the composition is a cyclic olefin copolymer (COC). A pharmaceutical composition for sublingually delivering an opioid comprising an opioid and a medium chain triglyceride, wherein the composition is contained in a container and where the substance of the container that is in contact with the composition is polypropylene. 7. The composition of claim 6, wherein the opioid is not methadone. The composition of claim 6, wherein said opioid is fentanyl. A composition according to any one of claims 5 to 8, wherein the container comprises a delivery device. The composition of claim 9, wherein the delivery device dispenses the composition with a single burst. The composition of claim 9, wherein the delivery device dispenses the composition in the form of a spray. The composition of claim 11, wherein said spray comprises liquid droplets having an average diameter of at least about 10 microns, preferably at least about 20 microns, more preferably from about 20 microns to about 200 microns, and most preferably from about 20 microns to about 100 μm. 13. The composition of claim 9, wherein the delivery device is not pressurized. The composition of claim 9, wherein the delivery device comprises seals and / or plungers, and where the substance of said seals and / or plungers that is in contact with the composition is1. Фармацевтическая композиция для сублингвальной доставки опиоида, содержащая опиоид и этанол.2. Композиция по п.1, которая дополнительно содержит глицерин.3. Композиция по п.1, где опиоид не является фентанилом.4. Композиция по п.1, где
