CASTRO- PALOMINO LARIA, JULIO CESAR,CAMACHO GOMEZ, JUAN ALBERTO,MENDOZA LIZALDEZ, ADELA
申请号:
CA2977905
公开号:
CA2977905A1
申请日:
2016.02.19
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to novel pyridine derivatives of formula (I) as A2B adenosine receptor antagonists and ligands of MT3 melatonin receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to the use of said for manufacturing a medicament for the treatment of pathological conditions or diseases that can improve by antagonizing the adenosine A2B receptor and by inhibition of MT3 melatonin receptor, such as respiratory disease, metabolic disorders, neurological disorders and cancer.