Julio Cesar CASTRO-PALOMINO LARIA,Juan Alberto CAMACHO GÓMEZ,Adela MENDOZA LIZALDEZ
申请号:
US15552039
公开号:
US20180037569A1
申请日:
2016.02.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to novel pyridine derivatives of formula (I):as A2B adenosine receptor antagonists and ligands of MT3 melatonin receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to the use of said for manufacturing a medicament for the treatment of pathological conditions or diseases that can improve by antagonizing the adenosine A2B receptor and by inhibition of MT3 melatonin receptor, such as respiratory disease, metabolic disorders, neurological disorders and cancer.