C. Simone Jude-Fishburn,Timothy A. Riley,Alberto N. Zacarias,Hema Gursahani
申请号：
US15047497
公开号：
US20160243111A1
申请日:
2016.02.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention provides opioid agonists covalently bound to a water-soluble oligomer having reduced potential for substance abuse and uses thereof. The compounds of the invention possess altered pharmacokinetic profiles relative to the opioid agonists alone, but are not subject to the risk of physical tampering that allows for the recovery and abuse of the opioid agonist associated with certain alternative delivery formulations.
