C SIMONE JUDE FISHBURN U S A,TIMOTHY A RILEY U S A,ALBERTO ZACARIAS U S A,HEMA GURSAHANI U S A
申请号:
IN2330/DELNP/2011
公开号:
IN2011DN02330A
申请日:
2011.03.30
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The invention provides opioid agonists covalently bound to a water-soluble oligomer having reduced potential for bstance abuse and uses thereof. The compounds of the invention possess altered pharmacokinetic profiles relative to the opioid agonists alone, but are not subject to the risk of physical tampering that allows for the recovery and abuse of the opioid agonist associated with certain alternative delivery formulations.