The invention disclosed herein is directed to compounds of Formula I [Formula should be entered here] and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, acute or chronic myeloid leukemia, melanoma, and other cancers. The invention also includes pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula I, or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, acute or chronic myeloid leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, acute or chronic myeloid leukemia, melanoma and other cancers through the administration of a therapeutically effective amount of a selective PPARα antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections.La présente invention concerne des composés de formule (I) et leurs sels pharmaceutiquement acceptables, qui sont utiles dans le traitement des cancers de la prostate, du sein, du côlon, du pancréas, de la leucémie lymphocytaire chronique humaine, de la leucémie myéloïde aiguë ou chronique, du mélanome et d'autres cancers. L'invention concerne également des compositions pharmaceutiques comportant une quantité thérapeutiquement efficace d'un composé de formule I ou un sel pharmaceutiquement acceptable de celui-ci. La présente invention concerne également des méthodes de traitement des cancers de la prostate, du sein, de l'ovaire, du foie, du rein, du côlon, du pancréas, de la leucémie lymphocytaire chronique humaine, de la leucémie myéloïde aiguë ou chronique, du mélano
