bispecific t-cell activating antigen binding molecule, isolated polynucleotide, encoded polypeptide, vector, host cell, production method, pharmaceutical composition, use, method of treating a disease in an individual and method for inducing lysis of a cell- target
ANNE FREIMOSER-GRUNDSCHOBER,CHRISTIANE JAEGER,EKKEHARD MOESSNER,OLIVER AST,PABLO UMANA,PETER BRUENKER,TANJA FAUTI
申请号：
BR112014003769
公开号：
BR112014003769A2
申请日:
2012.08.21
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
