Guohua Pan,Jacqueline M. Mason,Xin Wei,Miklos Feher
申请号：
US13807816
公开号：
US20130123273A1
申请日:
2011.07.04
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided herein are methods, uses and compositions for treating a patient with cancer wherein the cancer is characterized by a PTEN gene mutation. In particular embodiments, the methods comprise administering to the patient a composition comprising a therapeutically effective amount of a PLK4 antagonist, and identifying a patient that is likely to be responsive to PLK4 antagonist therapy, if PTEN gene mutation is present.
