PROCESS FOR OBTAINING AN IMPLANT OF FACIAL CELLULAR FILLER OF AUTOLOGOUS DERMAL FIBROBLASTS WITH AUTOLOGOUS FIBRIN FOR THE REGENERATION OF CREASES, ACNE SCARS, FACE/NECK WRINKLES AND SKIN DEFECTS.
The present invention provides a process for generating a dermo-aesthetic treatment for regenerating face wrinkles, which is formed by human analogous fibrin and autologous fibroblasts cultured in vitro and its application as filler in dermo-aesthetic treatments by means of the production of new human collagen from the implementation of autologous fibroblasts and human fibrin. Despite the latest advances in the surgical and non-surgical interventions, the dermo-aesthetic treatment still is a problem difficult to address due to the use of face fillers of synthetic/animal origin. The face cellular filler implant is defined as a novel process formed by a three-dimensional network of hydrophobic hydrogel (autologous human fibrin) in suspension, which promotes an encapsulation/support/transport of the autologous fibroblasts to be implanted in the papillary dermis. This three-dimensional structure in suspension of autologous human fibrin provides a high absorption of water, release of fact ors/nutriments and an excellent micro/macro viability environment of the autologous fibroblasts contained in this suspension: with the purpose of producing new collagen fibres in wrinkles, philtrum, acne scars, stretch marks.La presente invención provee un proceso para generar un tratamiento dermo estético para la regeneración de arrugas faciales compuesto de fibrina autóloga humana y fibroblastos autólogos cultivados in vitro y su aplicación como relleno en tratamientos dermo estéticos mediante la producción de nuevo colágeno humano a partir de la implantación de fibroblastos autólogos y fibrina humana. A pesar de los recientes avances en las intervenciones quiru´rgicas y no quiru´rgicas, los tratamientos dermo estéticos sigue siendo un problema de difícil abordaje debido al uso de rellenos faciales de origen sintético/animal. El implante de relleno celular facial se define como un proceso novedoso compuesto de una red tridimensional de un hidrogel hidrofóbico (fibrina humana autóloga)
