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基於低HER3表達預測對HER二聚化抑制劑的響應
专利权人:
GENENTECH INC.;F. HOFFMANN LA ROCHE AG
发明人:
AMLER, LUKAS, C.,BIRKNER, MERRILL,LIN, CHIN-YU,MOECKS, JOACHIM,STRAUSS, ANDREAS
申请号:
HK10107891.3
公开号:
HK1141586B
申请日:
2010.08.18
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
The present application describes the use of low HER3 as a selection criterion for treating patients with a HER inhibitor, such as pertuzumab. It also describes the use of high HER2:HER3 ratio as a selection criterion for treating cancer patients, such as ovarian cancer patients, with a HER inhibitor, such as pertuzumab. In addition, the application describes the use of high HER3 as a selection criterion for treating cancer patients with a chemotherapeutic agent, for instance gemcitabine.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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