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Prognozowanie odpowiedzi na inhibitor dimeryzacji HER oparte na niskiej ekspresji HER3
专利权人:
F. Hoffmann-La Roche AG;Genentech, Inc.
发明人:
AMLER, LUKAS C.,BIRKNER, MERRILL,LIN, CHIN-YU,MOECKS, JOACHIM,STRAUSS, ANDREAS
申请号:
PL08731126
公开号:
PL2132573T3
申请日:
2008.02.29
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
The present application describes the use of low HER3 as a selection criterion for treating patients with a HER inhibitor, such as pertuzumab. It also describes the use of high HER2:HER3 ratio as a selection criterion for treating cancer patients, such as ovarian cancer patients, with a HER inhibitor, such as pertuzumab. In addition, the application describes the use of high HER3 as a selection criterion for treating cancer patients with a chemotherapeutic agent, for instance gemcitabine.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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