PACKHAEUSER, CLAUDIA,STEIGER, NORBERT,LIEPOLD, BERND,KOSTELAC, DRAZEN,KNOBLOCH, MARTIN
申请号:
CA2763441
公开号:
CA2763441C
申请日:
2010.06.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to a pharmaceutical dosage form which comprises a soliddispersion product comprisingN--4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1--((phenylsulfanyl)methyl) propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvatethereof, atleast one pharmaceutically acceptable polymer, and at least onepharmaceutically acceptable solubilizer. The invention is furtherdirected to processes for preparing the pharmaceutical dosage form and to useof the dosage form for treating proliferative disorders.