A Chinese medicine composition for treating gastric reflux, comprising the following raw materials in parts by weight: 2-15 g of turmeric root tuber, 2-10 g of Gardenia jasminoides, 2-15 g of bamboo shavings, 2-10 g of Panax notoginseng, 3-12 g of ginger, 10-30 g of nacre, 3-12 g of fermented soybean, 5-20 g of cuttlebone, 3-12 g of honey-fried licorice root, 5-25 g of loquat leaf, 3-15 g of dried tangerine peel, 5-25 g of dandelion, and 5-25 g of jujube. The preparation method comprises the following steps: collecting and washing the raw materials; boiling the raw materials in water; combining, concentrating and cooling filtrates; adding ethanol so that the alcohol content is 20-80%; recovering ethanol; concentrating a supernatant into a thick paste; and saving the thick paste for later use. The thick paste is dried and prepared into corresponding formulations, including pills, tablets, powders, granules or soup bags.