The disclosure concerns a device for positioning a stent in a natural canal after the passage through an obstacle at the level of a target organ. The device includes a stent and a pusher tube and a guide. The guide is conceived to push the stent through the lumen of the natural canal and includes at least one flexible part having a predetermined longitudinal stiffness and a lateral flexibility consisting in a reversible deformation from a straight position to a bent position so as to follow the curve of the natural canal under the application of minimal external forces exerted by an operator. The disclosed device is particularly adapted to the technical field of urology.