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TREATMENT OF INFLAMMATORY DISEASES OF THE SKIN
专利权人:
ДЗЕ ЮНИВЕРСИТИ ОФ СИДНЕЙ (AU)
发明人:
ДЖЕКСОН Кристофер Джон (AU),СЮЭ Мэйлан (AU)
申请号:
RU2015103510
公开号:
RU2015103510A
申请日:
2013.07.04
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A method of treating a skin lesion characterized by the presence of hyperproliferative keratinocytes in an individual, comprising: providing an individual having a skin region that is characterized by the presence of hyperproliferative keratinocytes; contacting said skin region with a therapeutically effective amount of activated protein C (APS); as a result carry out the treatment of skin lesions in the specified individual. 2. A method according to claim 1, characterized in that said therapeutically effective amount of APS reduces inflammation in said area of the skin. A method according to claim 1 or 2, characterized in that said therapeutically effective amount of APS reduces apoptosis in said area of the skin. A method according to claim 1 or 2, characterized in that said therapeutically effective amount of APS does not inhibit the growth of normal keratinocytes or causes proliferation of normal keratinocytes. A method according to claim 1 or 2, characterized in that said therapeutically effective amount of APS is from 1 μg to 5 mg of APS in the skin area. A method according to claim 1 or 2, characterized in that the APS for making contact with the indicated area of the skin is provided in the form of a gel, cream, ointment, spray, lotion or similar composition adapted to make contact with the skin surface. A method according to claim 1 or 2, characterized in that the APS for contacting said skin area is in the form of a composition adapted for subcutaneous injection. A method according to claim 1 or 2, characterized in that said skin lesion is characterized by one or more of the following processes: apoptosis, inflammation, barrier violation1. Способ лечения поражения кожи, которое характеризуется присутствием гиперпролиферативных кератиноцитов, у индивидуума, включающий:обеспечение индивидуума, имеющего область кожи, которая характеризуется присутствием гиперпролиферативных кератиноцитов;осуществление контакта указанной области кожи с терапевтически эффект
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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